What does inducibility meaning?Asked by: Dr. Eliza Schaden I
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: capable of being formed, activated, or expressed in response to a stimulus especially of a molecular kind: as. a : formed by a cell in response to the presence of its substrate inducible enzymes — compare constitutive sense 1a.View full answer
In this regard, What does it mean for a protein to be inducible?
Inducible genes are those that have variable activity, depending on the needs of the cell. For example, the glucose transporter proteins that muscle cells produce in response to insulin are the product of inducible genes.
Likewise, people ask, What does the term allosteric mean?. : of, relating to, undergoing, or being a change in the shape and activity of a protein (such as an enzyme) that results from combination with another substance at a point other than the chemically active site.
Subsequently, question is, What is meant by inducible enzyme?
An adaptive enzyme or inducible enzyme is an enzyme that is expressed only under conditions in which it is clearly of adaptive value, as opposed to a constitutive enzyme which is produced all the time. The Inducible enzyme is used for the breaking-down of things in the cell.
What does Repressible mean?
Medical Definition of repressible
: capable of being repressed repressible enzymes controlled by their end products.
A repressible operon is one that is usually on but which can be repressed in the presence of a repressor molecule. The repressor binds to the operator in such a way that the movement or binding of RNA polymerase is blocked and transcription cannot proceed.
[ rĭ-prĕs′ə-bəl ] n. An enzyme whose production is generally continuous but can be halted if a particular substance is present in concentrations greater than normal.
Induce glycogen synthesis – When glucose levels are high, insulin induces the formation of glycogen by the activation of the hexokinase enzyme, which adds a phosphate group in glucose, thus resulting in a molecule that cannot exit the cell.
Corepressors are transcriptional regulators that are incapable of independent DNA binding, being recruited directly or indirectly by DNA-binding TFs to repress target gene expression.
An exoenzyme, or extracellular enzyme, is an enzyme that is secreted by a cell and functions outside that cell. Exoenzymes are produced by both prokaryotic and eukaryotic cells and have been shown to be a crucial component of many biological processes.
In this page you can discover 10 synonyms, antonyms, idiomatic expressions, and related words for allosteric, like: inducible, glycosylation, phosphorylation, signal-transduction, ap-1, , CDK2, dimerisation, actin-binding and adenylate.
Allosteric modulation occurs when an effector binds to an allosteric site (also known as a regulatory site) of an enzyme and alters the enzyme activity.
This type of inhibition is called allosteric inhibition . Competitive and noncompetitive inhibition affect the rate of reaction differently. Competitive inhibitors affect the initial rate but do not affect the maximal rate, whereas noncompetitive inhibitors affect the maximal rate.
The lac operon is under both negative and positive control. The mechanisms for these will be considered separately. 1. In negative control, the lacZYAgenes are switched off by repressor when the inducer is absent (signalling an absence of lactose).
Activators enhance the interaction between RNA polymerase and a particular promoter, encouraging the expression of the gene. Activators do this by increasing the attraction of RNA polymerase for the promoter, through interactions with subunits of the RNA polymerase or indirectly by changing the structure of the DNA.
Operon, genetic regulatory system found in bacteria and their viruses in which genes coding for functionally related proteins are clustered along the DNA. This feature allows protein synthesis to be controlled coordinately in response to the needs of the cell.
Prokaryotes. In prokaryotes, the term corepressor is used to denote the activating ligand of a repressor protein. For example, the E. coli tryptophan repressor (TrpR) is only able to bind to DNA and repress transcription of the trp operon when its corepressor tryptophan is bound to it.
The key difference between repressor and corepressor is that repressor protein directly binds to the operator sequence of the gene and inhibits gene expression while corepressor protein binds to the repressor protein and indirectly regulates the gene expression.
Lack of tryptophan increases the level of cAMP high, which leads to activation of CAP protein and gene expression. When tryptophan levels are low the repressor protein will not bind to the DNA and transcription will occur. When tryptophan is absent the activator protein will not bind and transcription will not occur.
When we eat food, glucose is absorbed from our gut into the bloodstream, raising blood glucose levels. This rise in blood glucose causes insulin to be released from the pancreas so glucose can move inside the cells and be used.
Insulin is an anabolic hormone that promotes glucose uptake, glycogenesis, lipogenesis, and protein synthesis of skeletal muscle and fat tissue through the tyrosine kinase receptor pathway.
Insulin production, secretion
Insulin is produced in the pancreas and is synthesized in the pancreas within the beta cells of the islets of Langerhans.
= A promoter is a sequence of DNA needed to turn a gene on or off. The process of transcription is initiated at the promoter. Usually found near the beginning of a gene, the promoter has a binding site for the enzyme used to make a messenger RNA (mRNA) molecule.
We lack operons because gene regulation is so complex that you could not possibly fit genes that code for regulation points close enough to the genes they regulate. Operons depend upon having the structural gene closely downstream, while Eukaryotic genes do not have this luxury due to these complex control mechanisms.
Operons are of two types, inducible and repressible.